Lusine Yaghjyan

Lusine Yaghjyan,

Associate Professor

Department: Department of Epidemiology
Business Phone: (352) 294-5940
Business Email: lyaghjyan@ufl.edu

Teaching Profile

Courses Taught
2018-2020
PHC7934 Seminar I: Epidemiology Past, Present, and Future
2015-2023
PHC7595 Introduction to Molecular Epidemiology
2014-2020
PHC6000 Epidemiology Methods I
2015-2017,2019-2020
PHC6946 Public Health Internship
2015-2017,2019-2020
PHC6601 Seminar in Contemporary Public Health Issues
2017-2019
PHC6011 Epidemiology Methods II
2015-2018
PHC6971 Research for Master’s Thesis
2018,2021
PHC7918 Independent Study
2017
PHC6945 Public Health Practicum
2014-2016
PHC6937 Special Topics in Public Health
2015,2022
PHC7979 Advanced Research
2014-2015
HSC4970 Public Health and Health Professions Senior Honors Thesis
2021-2023
PHC6941 MPH Applied Practice Experience
2022-2023
PHC7980 Research for Doctoral Dissertation

Research Profile

Dr. Yaghjyan’s research focuses on molecular epidemiology of breast cancer, benign breast disease, and mammographic breast density. Her areas of interest include tissue and circulating markers, contributions of gut microbiome to breast health, and the role of environmental factors in breast carcinogenesis.

Areas of Interest
  • Breast cancer risk factors
  • Breast cancer risk prediction
  • Cancer Screening
  • Endocrine disruptors
  • Environmental contributors to breast cancer
  • Gut microbiome and breast health
  • Molecular epidemiology
Open Researcher and Contributor ID (ORCID)

0000-0002-1626-5340

Publications

2024
Associations of early-life and adult anthropometric measures with the expression of stem cell markers CD44, CD24, and ALDH1A1 in women with benign breast biopsies
Cancer Epidemiology, Biomarkers & Prevention. [DOI] 10.1158/1055-9965.epi-23-1567.
2024
Associations of reproductive breast cancer risk factors with expression of stem cell markers in benign breast tissue.
Frontiers in oncology. 14 [DOI] 10.3389/fonc.2024.1354094. [PMID] 38577336.
2024
Effect of testosterone therapy on breast tissue composition and mammographic breast density in trans masculine individuals.
medRxiv : the preprint server for health sciences. [DOI] 10.1101/2024.01.09.24300987. [PMID] 38260574.
2024
Reproductive Factors Related to Childbearing and a Novel Automated Mammographic Measure, V
Cancer Epidemiology, Biomarkers & Prevention. 33(6):804-811 [DOI] 10.1158/1055-9965.epi-23-1318.
2023
Association of air pollution with postmenopausal breast cancer risk in UK Biobank.
Breast cancer research : BCR. 25(1) [DOI] 10.1186/s13058-023-01681-w. [PMID] 37443054.
2023
Associations of alcohol consumption with breast tissue composition
Breast Cancer Research. 25(1) [DOI] 10.1186/s13058-023-01638-z. [PMID] 36998083.
2023
Associations of gut microbiome with endogenous estrogen levels in healthy postmenopausal women
Cancer Causes & Control. 34(10):873-881 [DOI] 10.1007/s10552-023-01728-5.
2023
Associations of stem cell markers in benign breast tissue with subsequent breast cancer risk.
American journal of cancer research. 13(12):6280-6289 [PMID] 38187066.
2023
Correction: Associations of coffee/caffeine consumption with postmenopausal breast cancer risk and their interactions with postmenopausal hormone use
European Journal of Nutrition. 62(6):2707-2707 [DOI] 10.1007/s00394-023-03216-7.
2023
mTOR pathway candidate genes and energy intake interaction on breast cancer risk in Black women from the Women’s Circle of Health Study.
European journal of nutrition. 62(6):2593-2604 [DOI] 10.1007/s00394-023-03176-y. [PMID] 37209192.
2023
mTOR pathway candidate genes and obesity interaction on breast cancer risk in black women from the Women’s Circle of Health Study.
Cancer causes & control : CCC. 34(5):431-447 [DOI] 10.1007/s10552-022-01657-9. [PMID] 36790512.
2023
mTOR pathway candidate genes and physical activity interaction on breast cancer risk in black women from the women’s circle of health study.
Breast cancer research and treatment. 199(1):137-146 [DOI] 10.1007/s10549-023-06902-6. [PMID] 36882608.
2022
Associations of aspirin and other anti-inflammatory medications with breast cancer risk by the status of COX-2 expression
Breast Cancer Research. 24(1) [DOI] 10.1186/s13058-022-01575-3. [PMID] 36494710.
2022
Associations of coffee/caffeine consumption with postmenopausal breast cancer risk and their interactions with postmenopausal hormone use
European Journal of Nutrition. 61(7):3449-3459 [DOI] 10.1007/s00394-022-02899-8. [PMID] 35583696.
2022
Associations of established breast cancer risk factors with urinary estrogens in postmenopausal women
Cancer Causes & Control. 33(2):279-291 [DOI] 10.1007/s10552-021-01528-9.
2022
Associations of Oral Contraceptives with Mammographic Breast Density in Premenopausal Women.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 31(2):436-442 [DOI] 10.1158/1055-9965.EPI-21-0853. [PMID] 34862209.
2022
Reliability of CD44, CD24, and ALDH1A1 immunohistochemical staining: Pathologist assessment compared to quantitative image analysis.
Frontiers in medicine. 9 [DOI] 10.3389/fmed.2022.1040061. [PMID] 36590957.
2021
Association between rice consumption and risk of cancer incidence in the California Teachers Study
Breast Cancer Research and Treatment. 187(3):917-918 [DOI] 10.1007/s10549-021-06230-7.
2021
Association of Interactions Between Mammographic Density Phenotypes and Established Risk Factors With Breast Cancer Risk, by Tumor Subtype and Menopausal Status.
American journal of epidemiology. 190(1):44-58 [DOI] 10.1093/aje/kwaa131. [PMID] 32639533.
2021
Associations of reproductive breast cancer risk factors with breast tissue composition
Breast Cancer Research. 23(1) [DOI] 10.1186/s13058-021-01447-2. [PMID] 34225771.
2021
Early-Life and Adult Adiposity, Adult Height, and Benign Breast Tissue Composition.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 30(4):608-615 [DOI] 10.1158/1055-9965.EPI-20-1348. [PMID] 33288551.
2021
Gut microbiome, body weight, and mammographic breast density in healthy postmenopausal women.
Cancer causes & control : CCC. 32(7):681-692 [DOI] 10.1007/s10552-021-01420-6. [PMID] 33772705.
2020
Adolescent caffeine consumption and mammographic breast density in premenopausal women
European Journal of Nutrition. 59(4):1633-1639 [DOI] 10.1007/s00394-019-02018-0. [PMID] 31152213.
2020
Association of Adipose Tissue Distribution With Type 2 Diabetes in Breast Cancer Patients.
Breast cancer : basic and clinical research. 14 [DOI] 10.1177/1178223420972369. [PMID] 33281450.
2020
Associations of aspirin and other anti-inflammatory medications with mammographic breast density and breast cancer risk
Cancer Causes & Control. 31(9):827-837 [DOI] 10.1007/s10552-020-01321-0. [PMID] 32476101.
2020
COVID-19 in patients with cancer.
The Lancet. Oncology. 21(12) [DOI] 10.1016/S1470-2045(20)30668-9. [PMID] 33271096.
2020
Future Research Suggestions for Multigene Testing in Unselected Populations.
JAMA oncology. 6(5) [DOI] 10.1001/jamaoncol.2020.0128. [PMID] 32215575.
2020
LC-HRMS of derivatized urinary estrogens and estrogen metabolites in postmenopausal women.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1154 [DOI] 10.1016/j.jchromb.2020.122288. [PMID] 32769047.
2020
Microbiota composition in bilateral healthy breast tissue and breast tumors
Cancer Causes & Control. 31(11):1027-1038 [DOI] 10.1007/s10552-020-01338-5.
2020
Risk factors for delayed viral suppression on first-line antiretroviral therapy among persons living with HIV in Haiti, 2013-2017.
PloS one. 15(10) [DOI] 10.1371/journal.pone.0240817. [PMID] 33119631.
2020
Uterine cancer in breast cancer survivors: a systematic review
Breast Cancer Research and Treatment. 180(1):1-19 [DOI] 10.1007/s10549-019-05516-1.
2019
Associations of mammographic breast density with breast stem cell marker-defined breast cancer subtypes
Cancer Causes & Control. 30(10):1103-1111 [DOI] 10.1007/s10552-019-01207-w. [PMID] 31352658.
2019
Continuous Rural-Urban Coding for Cancer Disparity Studies: Is It Appropriate for Statistical Analysis?
International journal of environmental research and public health. 16(6) [DOI] 10.3390/ijerph16061076. [PMID] 30917515.
2019
Effect of Hospitalizations on Physical Activity Patterns in Mobility-Limited Older Adults.
Journal of the American Geriatrics Society. 67(2):261-268 [DOI] 10.1111/jgs.15631. [PMID] 30452084.
2019
Healthy behavioral choices and cancer screening in persons living with HIV/AIDS are different by sex and years since HIV diagnosis
Cancer Causes & Control. 30(3):281-290 [DOI] 10.1007/s10552-019-1135-3. [PMID] 30739240.
2019
Interaction between frailty and sex on mortality after elective abdominal aortic aneurysm repair.
Journal of vascular surgery. 70(6):1831-1843 [DOI] 10.1016/j.jvs.2019.01.086. [PMID] 31147120.
2018
Associations of coffee consumption and caffeine intake with mammographic breast density
Breast Cancer Research and Treatment. 169(1):115-123 [DOI] 10.1007/s10549-018-4667-4. [PMID] 29340883.
2018
Interactions between Alcohol Consumption and Adjuvant Hormone Therapy in Relation to Breast Cancer-Free Survival.
Journal of breast cancer. 21(2):158-164 [DOI] 10.4048/jbc.2018.21.2.158. [PMID] 29963111.
2018
Interactions of alcohol and postmenopausal hormone use in regards to mammographic breast density
Cancer Causes & Control. 29(8):751-758 [DOI] 10.1007/s10552-018-1053-9. [PMID] 29938357.
2018
Interactions of coffee consumption and postmenopausal hormone use in relation to breast cancer risk in UK Biobank
Cancer Causes & Control. 29(6):519-525 [DOI] 10.1007/s10552-018-1028-x.
2018
RE: The Association Between Dietary Quality and Overall and Cancer-Specific Mortality Among Cancer Survivors, NHANES III.
JNCI cancer spectrum. 2(3) [DOI] 10.1093/jncics/pky044. [PMID] 31361274.
2017
Association between air pollution and mammographic breast density in the Breast Cancer Surveilance Consortium.
Breast cancer research : BCR. 19(1) [DOI] 10.1186/s13058-017-0828-3. [PMID] 28381271.
2017
Interaction of mammographic breast density with menopausal status and postmenopausal hormone use in relation to the risk of aggressive breast cancer subtypes
Breast Cancer Research and Treatment. 165(2):421-431 [DOI] 10.1007/s10549-017-4341-2. [PMID] 28624977.
2017
Interactions of Family History of Breast Cancer with Radiotherapy in Relation to the Risk of Breast Cancer Recurrence.
Journal of breast cancer. 20(4):333-339 [DOI] 10.4048/jbc.2017.20.4.333. [PMID] 29285037.
2017
Tissue-based associations of mammographic breast density with breast stem cell markers.
Breast cancer research : BCR. 19(1) [DOI] 10.1186/s13058-017-0889-3. [PMID] 28851411.
2016
Adolescent fiber intake and mammographic breast density in premenopausal women.
Breast cancer research : BCR. 18(1) [DOI] 10.1186/s13058-016-0747-8. [PMID] 27520794.
2016
Associations of individual characteristics and lifestyle factors with metabolism of di-2-ethylhexyl phthalate in NHANES 2001-2012.
Environmental research. 149:23-31 [DOI] 10.1016/j.envres.2016.05.002. [PMID] 27174780.
2016
Maternal exposure to di-2-ethylhexylphthalate and adverse delivery outcomes: A systematic review.
Reproductive toxicology (Elmsford, N.Y.). 65:76-86 [DOI] 10.1016/j.reprotox.2016.07.002. [PMID] 27412369.
2016
Moving microbiota research toward establishing causal associations that represent viable targets for effective public health interventions.
Annals of epidemiology. 26(5):306-10 [DOI] 10.1016/j.annepidem.2016.03.011. [PMID] 27133768.
2016
Reproductive factors related to childbearing and mammographic breast density.
Breast cancer research and treatment. 158(2):351-9 [DOI] 10.1007/s10549-016-3884-y. [PMID] 27351801.
2015
Associations of urinary phthalates with body mass index, waist circumference and serum lipids among females: National Health and Nutrition Examination Survey 1999-2004.
International journal of obesity (2005). 39(6):994-1000 [DOI] 10.1038/ijo.2015.8. [PMID] 25644057.
2015
Mammographic breast density and breast cancer risk: interactions of percent density, absolute dense, and non-dense areas with breast cancer risk factors.
Breast cancer research and treatment. 150(1):181-9 [DOI] 10.1007/s10549-015-3286-6. [PMID] 25677739.
2015
Postmenopausal mammographic breast density and subsequent breast cancer risk according to selected tissue markers.
British journal of cancer. 113(7):1104-13 [DOI] 10.1038/bjc.2015.315. [PMID] 26335607.
2014
Racial disparities in healthy behaviors and cancer screening among breast cancer survivors and women without cancer: National Health Interview Survey 2005.
Cancer causes & control : CCC. 25(5):605-14 [DOI] 10.1007/s10552-014-0365-7. [PMID] 24634091.
2014
Serum Biomarkers of Polyfluoroalkyl Compound Exposure in Young Girls in Greater Cincinnati and the San Francisco Bay Area, USA
. 184:327-334
2014
Serum biomarkers of polyfluoroalkyl compound exposure in young girls in Greater Cincinnati and the San Francisco Bay Area, USA.
Environmental pollution (Barking, Essex : 1987). 184:327-34 [DOI] 10.1016/j.envpol.2013.09.008. [PMID] 24095703.
2013
Mammographic breast density and subsequent risk of breast cancer in postmenopausal women according to the time since the mammogram.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 22(6):1110-7 [DOI] 10.1158/1055-9965.EPI-13-0169. [PMID] 23603205.
2012
Mammographic breast density and breast cancer risk by menopausal status, postmenopausal hormone use and a family history of breast cancer.
Cancer causes & control : CCC. 23(5):785-90 [DOI] 10.1007/s10552-012-9936-7. [PMID] 22438073.
2012
Physical activity and mammographic breast density: a systematic review
. 135(2):367-380
2012
Physical activity and mammographic breast density: a systematic review.
Breast cancer research and treatment. 135(2):367-80 [DOI] 10.1007/s10549-012-2152-z. [PMID] 22814722.
2012
Relationship between breast cancer risk factors and mammographic breast density in the Fernald Community Cohort
. 106(5):996-1003
2012
Relationship between breast cancer risk factors and mammographic breast density in the Fernald Community Cohort.
British journal of cancer. 106(5):996-1003 [DOI] 10.1038/bjc.2012.1. [PMID] 22281662.
2012
Vitamin D and mammographic breast density: a systematic review.
Cancer causes & control : CCC. 23(1):1-13 [DOI] 10.1007/s10552-011-9851-3. [PMID] 21984232.
2011
Estrogens in the breast tissue: a systematic review.
Cancer causes & control : CCC. 22(4):529-40 [DOI] 10.1007/s10552-011-9729-4. [PMID] 21286801.
2011
Mammographic breast density and subsequent risk of breast cancer in postmenopausal women according to tumor characteristics.
Journal of the National Cancer Institute. 103(15):1179-89 [DOI] 10.1093/jnci/djr225. [PMID] 21795664.
2011
Mammographic breast density assessment: a methods study
Atlas Journal of Medical & Biological Sciences. 1(1):13-19

Grants

Jul 2023 ACTIVE
Stromal contributions to breast carcinogenesis
Role: Principal Investigator
Funding: NATL INST OF HLTH NCI
May 2021 ACTIVE
Biobanking for Breast Cancer Prevention and Disparity Research in Florida
Role: Principal Investigator
Funding: H LEE MOFFITT CANCER CTR & RES INST via FL DEPT OF HLTH BANKHEAD-COLEY CANCER RE
Dec 2019 ACTIVE
The role of breast stem cells in breast cancer etiology and risk prediction
Role: Principal Investigator
Funding: NATL INST OF HLTH NCI
Jul 2015 ACTIVE
Florida Academic Cancer Center Alliance Seed Grants
Role: Project Manager
Funding: UF HEALTH SHANDS HOSPITAL
Feb 2015 – Oct 2023
UF Health Cancer Center Pilot Project Grants funded through the Florida Consortium of National Cancer Institute Centers Program
Role: Project Manager
Funding: UF HEALTH SHANDS HOSPITAL
Jan 2015 – May 2024
UF Health Cancer Center Bridge Seed Grant funded through the Florida Consortium of National Cancer Institute Centers Program
Role: Project Manager
Funding: UF HEALTH SHANDS HOSPITAL

Education

Postdoctoral Research Associate
2009-2013 · Washington University in St. Louis
PhD Epidemiology
2004-2009 · University of Cincinnati
MPH
2003-2004 · American University of Armenia
MD
1991-1997 · Yerevan State Medical University

Contact Details

Phones:
Business:
(352) 294-5940
Emails:
Business:
lyaghjyan@ufl.edu
Addresses:
Business Mailing:
2004 MOWRY RD RM 4216
GAINESVILLE FL 32611