Ting-Yuan D Cheng

Ting-Yuan D Cheng,

Assistant Professor

Department: PHHP-COM EPIDEMIOLOGY
Business Phone: (352) 294-5495
Business Email: tingyuan.cheng@ufl.edu

About Ting-Yuan D Cheng

Dr. David Cheng is a cancer epidemiologist. He received his MHS degree in Epidemiology from Johns Hopkins Bloomberg School of Public Health and Ph.D. in Epidemiology from the University of Washington. He completed pre-doctoral training at Fred Hutchinson Cancer Research Center and post-doctoral training at Roswell Park Comprehensive Cancer Center. His main research areas are (1) Molecular pathological epidemiology in breast cancer etiology and outcome; (2) Gene-environmental interaction in nutrition-related pathways; (3) Cancer health disparities in relation to race/ethnicity and sex. He is the Principal Investigator of an NIH/NCI K07 Mentored Career Development Award (K07CA201334, 2016–2021) and a R37 MERIT Award (R37CA248371 2021-2028). These awards aim to understand the molecular mechanisms of how energy imbalance influences the etiology and outcomes of breast cancer. At UF, he is also devoted to developing a cancer survivor cohort in HealthStreet, a community-outreach research engagement program that has enrolled >10,000 participants in Florida. He maintains close collaboration with a number of institutes and cohort studies, including Roswell Park Comprehensive Cancer Center (where he is adjunct faculty), Kaiser Permanente Division of Research, and Women’s Health Initiatives. Dr. Cheng’s research has been published in a number of high-profile journals, including JNCI: Journal of the National Cancer Institute, American Journal of Epidemiology, and Carcinogenesis. He currently serves as Deputy Editor of the JNCI Cancer Spectrum.

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0002-4105-828X

Areas of Interest
  • Cancer epidemiology
  • Cancer survivorship
  • Energy balance and cancer
  • Health Disparities
  • Molecular pathological epidemiology

Publications

2021
Body fatness and breast cancer risk in relation to phosphorylated mTOR expression in a sample of predominately Black women.
Breast cancer research : BCR. 23(1) [DOI] 10.1186/s13058-021-01458-z. [PMID] 34330319.
2021
Breast Tumor Microenvironment in Black Women: A Distinct Signature of CD8+ T Cell Exhaustion.
Journal of the National Cancer Institute. [DOI] 10.1093/jnci/djaa215. [PMID] 33395700.
2020
Association of Adipose Tissue Distribution With Type 2 Diabetes in Breast Cancer Patients.
Breast cancer : basic and clinical research. 14 [DOI] 10.1177/1178223420972369. [PMID] 33281450.
2020
Association of Diet Quality and Physical Activity on Obesity-Related Cancer Risk and Mortality in Black Women: Results from the Women’s Health Initiative
Cancer Epidemiology Biomarkers & Prevention. 29(3):591-598 [DOI] 10.1158/1055-9965.epi-19-1063.
2020
Associations between Plasma Choline Metabolites and Genetic Polymorphisms in One-Carbon Metabolism in Postmenopausal Women: The Women’s Health Initiative Observational Study.
The Journal of nutrition. 150(11):2874-2881 [DOI] 10.1093/jn/nxaa266. [PMID] 32939549.
2020
Body fatness and mTOR pathway activation of breast cancer in the Women’s Circle of Health Study.
NPJ breast cancer. 6 [DOI] 10.1038/s41523-020-00187-4. [PMID] 33024820.
2020
FOXA1 Protein Expression in ER+ and ER- Breast Cancer in Relation to Parity and Breastfeeding in Black and White Women.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 29(2):379-385 [DOI] 10.1158/1055-9965.EPI-19-0787. [PMID] 31871111.
2020
FOXA1 Protein Expression in ER+ and ER− Breast Cancer in Relation to Parity and Breastfeeding in Black and White Women
Cancer Epidemiology Biomarkers & Prevention. 29(2):379-385 [DOI] 10.1158/1055-9965.epi-19-0787.
2020
Risk of Breast Cancer Associated with Estrogen DNA Adduct Biomarker
Cancer Epidemiology Biomarkers & Prevention. 29(10):2096-2099 [DOI] 10.1158/1055-9965.epi-20-0133.
2018
Smoking, Sex, and Non-Small Cell Lung Cancer: Steroid Hormone Receptors in Tumor Tissue (S0424).
Journal of the National Cancer Institute. 110(7):734-742 [DOI] 10.1093/jnci/djx260. [PMID] 29346580.
2017
Serum 25-hydroxyvitamin D concentrations and lung cancer risk in never-smoking postmenopausal women.
Cancer causes & control : CCC. 28(10):1053-1063 [DOI] 10.1007/s10552-017-0956-1. [PMID] 28900765.
2016
Genetic variants in the mTOR pathway and breast cancer risk in African American women.
Carcinogenesis. 37(1):49-55 [DOI] 10.1093/carcin/bgv160. [PMID] 26577839.
2016
Genetic variants in the mTOR pathway and interaction with body size and weight gain on breast cancer risk in African-American and European American women.
Cancer causes & control : CCC. 27(8):965-76 [DOI] 10.1007/s10552-016-0774-x. [PMID] 27314662.
2016
The International Epidemiology of Lung Cancer: Latest Trends, Disparities, and Tumor Characteristics.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 11(10):1653-71 [DOI] 10.1016/j.jtho.2016.05.021. [PMID] 27364315.
2016
Urinary Excretion of the β-Adrenergic Feed Additives Ractopamine and Zilpaterol in Breast and Lung Cancer Patients.
Journal of agricultural and food chemistry. 64(40):7632-7639 [PMID] 27641640.
View on: PubMed

Grants

Feb 2021 ACTIVE
Energy Balance, mTOR pathway signaling, and breast cancer prognosis
Role: Principal Investigator
Funding: NATL INST OF HLTH NCI
Jul 2020 ACTIVE
Together Transforming and Translating Discovery to Improve Health
Role: Project Manager
Funding: NATL INST OF HLTH NCATS
Jan 2017 – Jun 2021
mTOR pathway in breast cancer subtypes by race: A molecular pathological study
Role: Principal Investigator
Funding: NATL INST OF HLTH NCI

Education

PhD
2013 · University of Washington
MHS
2007 · Johns Hopkins University

Teaching Profile

Courses Taught
2018-2021
PHC6711 Measurement in Epidemiology and Outcomes Research
2020-2021
PHC7979 Advanced Research
2019-2021
PHC7918 Independent Study
2018-2019
HSC4970 Public Health and Health Professions Senior Honors Thesis
2018-2019
PHC6971 Research for Master’s Thesis
2017
PHC6601 Seminar in Contemporary Public Health Issues
2017
PHC6946 Public Health Internship
2017
PHC6001 Principles of Epidemiology in Public Health
2021
PHC6941 MPH Applied Practice Experience

Contact Details

Phones:
Business:
(352) 294-5495
Emails: